04.2.2009

VITAMIN SUPPLEMENTS TO PREVENT CANCER: NICOTINAMIDE, NIACIN AND PYRIDOXINE

Vitamin B3 – Nicotinamide, Niacin

Vitamin B3 is essential in maintaining good blood circulation, dilating blood vessels and energy production. It also enhances the effectiveness of chemotherapy treatment by tripling the time chemotherapy drugs stay in the bloodstream. Vitamin B3 decreases the toxicity of the commonly used chemotherapy medication, Cisplatin. It increases anti-tumour activity and vitamin B3 and aspirin given with radiation therapy increases the body’s anti-tumour resistance.

Vitamin B3 also enhances the effectiveness of the cancer drug L-pam. It doubles the effectiveness of the drug if given by injection, one hour before L-pam.

During malignancy or cell proliferation, the cancer cell metabolizes glucose anaerobically (without oxygen) rather than aerobically (with oxygen). This results in an energy deficiency. Vitamin B3 partly solves this problem and thus reduces cancer growth and spread, by normalizing cancer cell energetics.

Only moderate amounts of vitamin B3 occur in foods as pure niacin; other niacin is converted from the amino acid tryptophan. The best sources of vitamin B3 are liver and other organ meats, poultry, fish and peanuts, all of which have both niacin and tryptophan. Yeast, dried beans, and peas, wheat germ, avocados, dates, figs, and prunes are good sources of niacin.

Vitamin B6 – Pyridoxine

Vitamin B6 is involved in a majority of the body’s functions. It acts as a cofactor in several hundred different biochemical reactions in nearly every part of the body. It is necessary for the production of hydrochloric acid, the absorption of fats and protein, maintains sodium/potassium balance (preventing fluid retention) and promotes red blood cell formation. It is also important for energy production, for proper functioning of the brain, formation of hemoglobin and for optimal immune function and antibody production.

Vitamin B6 plays a role in cancer immunity and aids in the prevention of arteriosclerosis. It is needed for the synthesis of nucleic acids RNA and DNA that contain the genetic instructions for the reproduction of all cells, and for normal cellular growth. It can trigger the production of other substances, stopping cancer growth. It may help to prevent lung cancer and skin cancer. Women with cervical cancer are thought to have very low levels of Vitamin B6 in their bodies.

Vitamin B6 deficiency may increase susceptibility to virus induced tumour growth. Survival time may be increased in people with cervical carcinoma, Stage Two endometrial carcinoma and Stage Two bladder cancer and breast cancer when supplemented with pyridoxine. A long-term deficiency of Vitamin B6 is thought to contribute to a depressed immune system as this vitamin is integral in the production of immune system cells.

Good sources of vitamin B6 include brewer’s yeast, fish, chicken, spinach, sunflower seeds, walnuts, wheat-germ, peas, carrots, halibut, whole-grains, liver and vegetables.

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